Opening of the mitochondrial permeability transition pore links mitochondrial dysfunction to insulin resistance in skeletal muscle()

Insulin resistance is associated with mitochondrial dysfunction, but the mechanism by which mitochondria inhibit insulin-stimulated glucose uptake into the cytoplasm is unclear. The mitochondrial permeability transition pore (mPTP) is a protein complex that facilitates the exchange of molecules betw...

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Autori principali: Taddeo, E.P., Laker, R.C., Breen, D.S., Akhtar, Y.N., Kenwood, B.M., Liao, J.A., Zhang, M., Fazakerley, D.J., Tomsig, J.L., Harris, T.E., Keller, S.R., Chow, J.D., Lynch, K.R., Chokki, M., Molkentin, J.D., Turner, N., James, D.E., Yan, Z., Hoehn, K.L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2013
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953683/
https://ncbi.nlm.nih.gov/pubmed/24634818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2013.11.003
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