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Selective Allosteric Enhancement of Agonist Binding and Function at Human A(3) Adenosine Receptors by a Series of Imidazoquinoline Derivatives
We have identified a series of 1H-imidazo-[4,5-c]quinolines as selective allosteric enhancers of human A(3) adenosine receptors. Several of these compounds potentiated both the potency and maximal efficacy of agonist-induced responses and selectively decreased the dissociation of the agonist N(6)-(4...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2002
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3953617/ https://ncbi.nlm.nih.gov/pubmed/12065758 |
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