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Evidence of Native α-Synuclein Conformers in the Human Brain

α-Synuclein aggregation is central to the pathogenesis of several brain disorders. However, the native conformations and functions of this protein in the human brain are not precisely known. The native state of α-synuclein was probed by gel filtration coupled with native gradient gel separation, an...

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Detalhes bibliográficos
Main Authors: Gould, Neal, Mor, Danielle E., Lightfoot, Richard, Malkus, Kristen, Giasson, Benoit, Ischiropoulos, Harry
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953303/
https://ncbi.nlm.nih.gov/pubmed/24474688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C113.538249
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