Sterol Regulatory Element-binding Protein (SREBP) Cleavage Regulates Golgi-to-Endoplasmic Reticulum Recycling of SREBP Cleavage-activating Protein (SCAP)

Sterol regulatory element-binding protein (SREBP) transcription factors are central regulators of cellular lipogenesis. Release of membrane-bound SREBP requires SREBP cleavage-activating protein (SCAP) to escort SREBP from the endoplasmic reticulum (ER) to the Golgi for cleavage by site-1 and site-2...

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Autores principales: Shao, Wei, Espenshade, Peter J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Lipids
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953268/
https://ncbi.nlm.nih.gov/pubmed/24478315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.545699
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