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Dissociated Presenilin-1 and TACE Processing of ErbB4 in Lung Alveolar Type II Cell Differentiation
Neuregulin (NRG) stimulation of ErbB4 signaling is important for type II cell surfactant synthesis. ErbB4 may mediate gene expression via a non-canonical pathway involving enzymatic cleavage releasing its intracellular domain (4ICD) for nuclear trafficking and gene regulation. The accepted model for...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3953239/ https://ncbi.nlm.nih.gov/pubmed/24462774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2014.01.015 |
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