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Presenilin-1 Processing of ErbB4 in Fetal Type II Cells is Necessary for Control of Fetal Lung Maturation

Maturation of pulmonary fetal type II cells to initiate adequate surfactant production is crucial for postnatal respiratory function. Little is known about specific mechanisms of signal transduction controlling type II cell maturation. The ErbB4 receptor and its ligand neuregulin (NRG) are critical...

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Detalhes bibliográficos
Main Authors: Hoeing, Kristina, Zscheppang, Katja, Mujahid, Sana, Murray, Sandy, Volpe, MaryAnn V., Dammann, Christiane E. L., Nielsen, Heber C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046222/
https://ncbi.nlm.nih.gov/pubmed/21195117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2010.12.017
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