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Presenilin-1 Processing of ErbB4 in Fetal Type II Cells is Necessary for Control of Fetal Lung Maturation

Maturation of pulmonary fetal type II cells to initiate adequate surfactant production is crucial for postnatal respiratory function. Little is known about specific mechanisms of signal transduction controlling type II cell maturation. The ErbB4 receptor and its ligand neuregulin (NRG) are critical...

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Autores principales: Hoeing, Kristina, Zscheppang, Katja, Mujahid, Sana, Murray, Sandy, Volpe, MaryAnn V., Dammann, Christiane E. L., Nielsen, Heber C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046222/
https://ncbi.nlm.nih.gov/pubmed/21195117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2010.12.017
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