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Reduction of the HIV Protease Inhibitor-Induced ER Stress and Inflammatory Response by Raltegravir in Macrophages

BACKGROUND: HIV protease inhibitor (PI), the core component of highly active antiretroviral treatment (HAART) for HIV infection, has been implicated in HAART-associated cardiovascular complications. Our previous studies have demonstrated that activation of endoplasmic reticulum (ER) stress is linked...

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Huvudupphovsmän: Zhang, Xiaoxuan, Cao, Risheng, Liu, Runping, Zhao, Renping, Huang, Yi, Gurley, Emily C., Hylemon, Phillip B., Pandak, William M., Wang, Guangji, Zhang, Luyong, Li, Xiaokun, Zhou, Huiping
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953206/
https://ncbi.nlm.nih.gov/pubmed/24625618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090856
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