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NOD2/RICK-Dependent β-Defensin 2 Regulation Is Protective for Nontypeable Haemophilus influenzae-Induced Middle Ear Infection

Middle ear infection, otitis media (OM), is clinically important due to the high incidence in children and its impact on the development of language and motor coordination. Previously, we have demonstrated that the human middle ear epithelial cells up-regulate β-defensin 2, a model innate immune mol...

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Detalhes bibliográficos
Main Authors: Woo, Jeong-Im, Oh, Sejo, Webster, Paul, Lee, Yoo Jin, Lim, David J., Moon, Sung K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953203/
https://ncbi.nlm.nih.gov/pubmed/24625812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090933
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