Synergistic effect of interleukin 1 alpha on nontypeable Haemophilus influenzae-induced up-regulation of human beta-defensin 2 in middle ear epithelial cells

BACKGROUND: We recently showed that beta-defensins have antimicrobial activity against nontypeable Haemophilus influenzae (NTHi) and that interleukin 1 alpha (IL-1 alpha) up-regulates the transcription of beta-defensin 2 (DEFB4 according to new nomenclature of the Human Genome Organization) in human...

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Autori principali: Moon, Sung-Kyun, Lee, Haa-Yung, Pan, Huiqi, Takeshita, Tamotsu, Park, Raekil, Cha, Kiweon, Andalibi, Ali, Lim, David J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2006
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1368979/
https://ncbi.nlm.nih.gov/pubmed/16433908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-6-12
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