NOD2/RICK-Dependent β-Defensin 2 Regulation Is Protective for Nontypeable Haemophilus influenzae-Induced Middle Ear Infection

Middle ear infection, otitis media (OM), is clinically important due to the high incidence in children and its impact on the development of language and motor coordination. Previously, we have demonstrated that the human middle ear epithelial cells up-regulate β-defensin 2, a model innate immune mol...

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Main Authors: Woo, Jeong-Im, Oh, Sejo, Webster, Paul, Lee, Yoo Jin, Lim, David J., Moon, Sung K.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953203/
https://ncbi.nlm.nih.gov/pubmed/24625812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090933
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