Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation.

The transcription factor E2F has been implicated in controlling the activation of multiple genes associated with cell proliferation. E2F-1, which is a component of E2F, can promote oncogenesis when transfected into REF cells. The transformation caused by E2F-1 correlates with constitutive overexpres...

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Detaylı Bibliyografya
Asıl Yazarlar: Singh, P, Wong, S H, Hong, W
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1994
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC395230/
https://ncbi.nlm.nih.gov/pubmed/8045262
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