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A conservation and rigidity based method for detecting critical protein residues

BACKGROUND: Certain amino acids in proteins play a critical role in determining their structural stability and function. Examples include flexible regions such as hinges which allow domain motion, and highly conserved residues on functional interfaces which allow interactions with other proteins. De...

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Detalhes bibliográficos
Main Authors: Akbal-Delibas, Bahar, Jagodzinski, Filip, Haspel, Nurit
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3952096/
https://ncbi.nlm.nih.gov/pubmed/24565061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-13-S1-S6
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