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A conservation and rigidity based method for detecting critical protein residues

BACKGROUND: Certain amino acids in proteins play a critical role in determining their structural stability and function. Examples include flexible regions such as hinges which allow domain motion, and highly conserved residues on functional interfaces which allow interactions with other proteins. De...

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Main Authors: Akbal-Delibas, Bahar, Jagodzinski, Filip, Haspel, Nurit
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2013
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3952096/
https://ncbi.nlm.nih.gov/pubmed/24565061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-13-S1-S6
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