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A conservation and rigidity based method for detecting critical protein residues

BACKGROUND: Certain amino acids in proteins play a critical role in determining their structural stability and function. Examples include flexible regions such as hinges which allow domain motion, and highly conserved residues on functional interfaces which allow interactions with other proteins. De...

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Bibliographische Detailangaben
Hauptverfasser: Akbal-Delibas, Bahar, Jagodzinski, Filip, Haspel, Nurit
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3952096/
https://ncbi.nlm.nih.gov/pubmed/24565061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-13-S1-S6
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