Synthetic lethality with fibrillarin identifies NOP77p, a nucleolar protein required for pre-rRNA processing and modification.

The nucleolar protein fibrillarin (encoded by the NOP1 gene in yeast), is required for many post-transcriptional steps in yeast ribosome synthesis. A screen for mutations showing synthetic lethality with a temperature sensitive nop1-5 allele led to the identification of the NOP77 gene. NOP77 is esse...

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Vydáno v:	EMBO J
Hlavní autoři:	Bergès, T, Petfalski, E, Tollervey, D, Hurt, E C
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Publishing Group 1994
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395205/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8039506/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06612.x
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