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Senescence and the Pro-tumorigenic Stroma

Hayflick and Moorhead first described senescence in the late 1960’s as a permanent growth arrest that primary cells underwent after a defined number of cellular divisions in culture. This observation gave rise to the hypothesis that cells contained an internal counting mechanism that limited cellula...

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Bibliografiske detaljer
Main Authors: Alspach, Elise, Fu, Yujie, Stewart, Sheila A.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951899/
https://ncbi.nlm.nih.gov/pubmed/24579734
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