RasGRP3, a Ras activator, contributes to signaling and the tumorigenic phenotype in human melanoma

RasGRP3, an activator for H-Ras, R-Ras and Rap1/2, has emerged as an important mediator of signaling downstream from receptor coupled phosphoinositide turnover in B and T cells. Here, we report that RasGRP3 showed a high level of expression in multiple human melanoma cell lines as well as in a subse...

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Detalhes bibliográficos
Main Authors: Yang, Dazhi, Tao, Juan, Li, Luowei, Kedei, Noemi, Tóth, Zsuzsanna E., Czap, Alexandra, Velasquez, Julia F., Mihova, Daniela, Michalowski, Aleksandra M., Yuspa, Stuart H., Blumberg, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951887/
https://ncbi.nlm.nih.gov/pubmed/21602881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.166
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