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Function of RasGRP3 in the formation and progression of human breast cancer
INTRODUCTION: Ras guanine nucleotide exchange factors (RasGEFs) mediate the activation of the Ras signaling pathway that is over activated in many human cancers. The RasGRP3, an activator of H-Ras and R-Ras protein exerts oncogenic effects and the overexpression of the protein is observed in numerou...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4113147/ https://ncbi.nlm.nih.gov/pubmed/24779681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-96 |
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