Function of RasGRP3 in the formation and progression of human breast cancer

INTRODUCTION: Ras guanine nucleotide exchange factors (RasGEFs) mediate the activation of the Ras signaling pathway that is over activated in many human cancers. The RasGRP3, an activator of H-Ras and R-Ras protein exerts oncogenic effects and the overexpression of the protein is observed in numerou...

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Bibliografiske detaljer
Main Authors: Nagy, Zsuzsanna, Kovács, Ilona, Török, Miklós, Tóth, Dezső, Vereb, György, Buzás, Krisztina, Juhász, István, Blumberg, Peter M, Bíró, Tamás, Czifra, Gabriella
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113147/
https://ncbi.nlm.nih.gov/pubmed/24779681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-96
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