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RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells

The mechanistic target of rapamycin (mTOR) in complex 1 (mTORC1) pathway integrates signals generated by hormones and nutrients to control cell growth and metabolism. The activation state of mTORC1 is regulated by a variety of GTPases including Rheb and Rags. Recently, Rho1, the yeast ortholog of Rh...

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Detalhes bibliográficos
Main Authors: Gordon, Bradley S., Kazi, Abid A., Coleman, Catherine S., Dennis, Michael D., Chau, Vincent, Jefferson, Leonard S., Kimball, Scot R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951878/
https://ncbi.nlm.nih.gov/pubmed/24316235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2013.11.035
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