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Use of historical control data for assessing treatment effects in clinical trials

Clinical trials rarely, if ever, occur in a vacuum. Generally, large amounts of clinical data are available prior to the start of a study, particularly on the current study’s control arm. There is obvious appeal in using (i.e., ‘borrowing’) this information. With historical data providing informatio...

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Detalhes bibliográficos
Main Authors: Viele, Kert, Berry, Scott, Neuenschwander, Beat, Amzal, Billy, Chen, Fang, Enas, Nathan, Hobbs, Brian, Ibrahim, Joseph G., Kinnersley, Nelson, Lindborg, Stacy, Micallef, Sandrine, Roychoudhury, Satrajit, Thompson, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951812/
https://ncbi.nlm.nih.gov/pubmed/23913901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pst.1589
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