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Adaptive adjustment of the randomization ratio using historical control data

BACKGROUND: Prospective trial design often occurs in the presence of “acceptable” [1] historical control data. Typically this data is only utilized for treatment comparison in a posteriori retrospective analysis to estimate population-averaged effects in a random-effects meta-analysis. PURPOSE: We p...

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書誌詳細
主要な著者: Hobbs, Brian P., Carlin, Bradley P., Sargent, Daniel J.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856641/
https://ncbi.nlm.nih.gov/pubmed/23690095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774513483934
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