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Adaptive adjustment of the randomization ratio using historical control data
BACKGROUND: Prospective trial design often occurs in the presence of “acceptable” [1] historical control data. Typically this data is only utilized for treatment comparison in a posteriori retrospective analysis to estimate population-averaged effects in a random-effects meta-analysis. PURPOSE: We p...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3856641/ https://ncbi.nlm.nih.gov/pubmed/23690095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774513483934 |
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