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Function, targets and evolution of Caenorhabditis elegans piRNAs
Piwi-interacting RNAs (piRNAs) are small RNAs required to maintain germline integrity and fertility but their mechanism of action is poorly understood. Here we demonstrate that C. elegans piRNAs silence transcripts in trans through imperfectly complementary sites. Target silencing is independent of...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3951736/ https://ncbi.nlm.nih.gov/pubmed/22700655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1220952 |
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