DEPS-1 is required for piRNA-dependent silencing and PIWI condensate organisation in Caenorhabditis elegans

Membraneless organelles are sites for RNA biology including small non-coding RNA (ncRNA) mediated gene silencing. How small ncRNAs utilise phase separated environments for their function is unclear. We investigated how the PIWI-interacting RNA (piRNA) pathway engages with the membraneless organelle...

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Udgivet i:Nat Commun
Main Authors: Suen, Kin Man, Braukmann, Fabian, Butler, Richard, Bensaddek, Dalila, Akay, Alper, Lin, Chi-Chuan, Milonaitytė, Dovilė, Doshi, Neel, Sapetschnig, Alexandra, Lamond, Angus, Ladbury, John Edward, Miska, Eric Alexander
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7447803/
https://ncbi.nlm.nih.gov/pubmed/32843637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18089-1
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