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Negative regulation by PD-L1 during drug-specific priming of IL-22 secreting T-cells and the influence of PD-1 on effector T-cell function
Activation of PD-1 on T-cells is thought to inhibit antigen-specific T-cell priming and regulate T-cell differentiation. Thus, we sought to measure the drug-specific activation of naïve T-cells after perturbation of PD-L1/2/PD-1 binding and investigate whether PD-1 signaling influences the different...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3951492/ https://ncbi.nlm.nih.gov/pubmed/24510967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302720 |
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