The site of 3' end formation of histone messenger RNA is a fixed distance from the downstream element recognized by the U7 snRNP.

Two conserved elements direct the 3' end processing of histone messenger RNA: a stem-loop structure immediately upstream of the site of cleavage and the histone downstream element (HDE), located 12-19 nucleotides downstream of the stem-loop in the premessenger RNA. We studied the role of these...

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Bibliographic Details
Main Authors: Scharl, E C, Steitz, J A
Format: Artigo
Language:Inglês
Published: 1994
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC395109/
https://ncbi.nlm.nih.gov/pubmed/8194533
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