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Membrane protein topology: effects of delta mu H+ on the translocation of charged residues explain the 'positive inside' rule.

The membrane electrochemical potential is critical for the export of most periplasmic proteins in Escherichia coli. Its exact role during insertion of integral inner membrane proteins, however, remains obscure. Using derivatives of the inner membrane protein leader peptidase (Lep), we now show that...

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Detalles Bibliográficos
Autores principales: Andersson, H, von Heijne, G
Formato: Artigo
Lenguaje:Inglês
Publicado: 1994
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC395088/
https://ncbi.nlm.nih.gov/pubmed/8194517
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