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Models that include supercoiling of topological domains reproduce several known features of interphase chromosomes

Understanding the structure of interphase chromosomes is essential to elucidate regulatory mechanisms of gene expression. During recent years, high-throughput DNA sequencing expanded the power of chromosome conformation capture (3C) methods that provide information about reciprocal spatial proximity...

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Detalhes bibliográficos
Main Authors: Benedetti, Fabrizio, Dorier, Julien, Burnier, Yannis, Stasiak, Andrzej
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950722/
https://ncbi.nlm.nih.gov/pubmed/24366878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1353
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