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Nucleosomes accelerate transcription factor dissociation
Transcription factors (TF) bind DNA-target sites within promoters to activate gene expression. TFs target their DNA-recognition sequences with high specificity by binding with resident times of up to hours in vitro. However, in vivo TFs can exchange on the order of seconds. The factors that regulate...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2014
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| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3950707/ https://ncbi.nlm.nih.gov/pubmed/24353316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1319 |
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