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Dissociation rate compensation mechanism for budding yeast pioneer transcription factors

Nucleosomes restrict the occupancy of most transcription factors (TF) by reducing binding and accelerating dissociation, while a small group of TFs have high affinities to nucleosome-embedded sites and facilitate nucleosome displacement. To understand this process mechanistically, we investigated tw...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Donovan, Benjamin T, Chen, Hengye, Jipa, Caroline, Bai, Lu, Poirier, Michael G
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449090/
https://ncbi.nlm.nih.gov/pubmed/30888317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.43008
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