Structural basis for promoter specificity switching of RNA polymerase by a phage factor

Transcription of DNA to RNA by DNA-dependent RNA polymerase (RNAP) is the first step of gene expression and a major regulation point. Bacteriophages hijack their host's transcription machinery and direct it to serve their needs. The gp39 protein encoded by Thermus thermophilus phage P23-45 bind...

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Bibliografiske detaljer
Main Authors: Tagami, Shunsuke, Sekine, Shun-ichi, Minakhin, Leonid, Esyunina, Daria, Akasaka, Ryogo, Shirouzu, Mikako, Kulbachinskiy, Andrey, Severinov, Konstantin, Yokoyama, Shigeyuki
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950348/
https://ncbi.nlm.nih.gov/pubmed/24589779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.233916.113
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