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A novel phage-encoded transcription antiterminator acts by suppressing bacterial RNA polymerase pausing

Gp39, a small protein encoded by Thermus thermophilus phage P23–45, specifically binds the host RNA polymerase (RNAP) and inhibits transcription initiation. Here, we demonstrate that gp39 also acts as an antiterminator during transcription through intrinsic terminators. The antitermination activity...

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Detalhes bibliográficos
Main Authors: Berdygulova, Zhanna, Esyunina, Daria, Miropolskaya, Nataliya, Mukhamedyarov, Damir, Kuznedelov, Konstantin, Nickels, Bryce E., Severinov, Konstantin, Kulbachinskiy, Andrey, Minakhin, Leonid
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351154/
https://ncbi.nlm.nih.gov/pubmed/22238378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1285
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