A novel phage-encoded transcription antiterminator acts by suppressing bacterial RNA polymerase pausing

Gp39, a small protein encoded by Thermus thermophilus phage P23–45, specifically binds the host RNA polymerase (RNAP) and inhibits transcription initiation. Here, we demonstrate that gp39 also acts as an antiterminator during transcription through intrinsic terminators. The antitermination activity...

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Bibliographische Detailangaben
Hauptverfasser: Berdygulova, Zhanna, Esyunina, Daria, Miropolskaya, Nataliya, Mukhamedyarov, Damir, Kuznedelov, Konstantin, Nickels, Bryce E., Severinov, Konstantin, Kulbachinskiy, Andrey, Minakhin, Leonid
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Molecular Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351154/
https://ncbi.nlm.nih.gov/pubmed/22238378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1285
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