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Probabilistic Splicing of Dscam1 Establishes Identity at the Level of Single Neurons
The Drosophila Dscam1 gene encodes a vast number of cell recognition molecules through alternative splicing. These exhibit isoform-specific homophilic binding and regulate self-avoidance, the tendency of neurites from the same cell to repel one another. Genetic experiments indicate that different ce...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3950301/ https://ncbi.nlm.nih.gov/pubmed/24267895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.10.018 |
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