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Probabilistic Splicing of Dscam1 Establishes Identity at the Level of Single Neurons

The Drosophila Dscam1 gene encodes a vast number of cell recognition molecules through alternative splicing. These exhibit isoform-specific homophilic binding and regulate self-avoidance, the tendency of neurites from the same cell to repel one another. Genetic experiments indicate that different ce...

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Detalhes bibliográficos
Main Authors: Miura, Satoru K., Martins, André, Zhang, Kelvin X., Graveley, Brenton R., Zipursky, S. Lawrence
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950301/
https://ncbi.nlm.nih.gov/pubmed/24267895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.10.018
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