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Targeting the ABCG2-overexpressing multidrug resistant (MDR) cancer cells by PPARγ agonists
BACKGROUND AND PURPOSE: Multidrug resistance (MDR), usually mediated by overexpression of efflux transporters such as P-gp, ABCG2 and/or MRP1, remains a major obstacle hindering successful cancer chemotherapy. There has been great interest in the development of inhibitors towards these transporters...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3949660/ https://ncbi.nlm.nih.gov/pubmed/24032744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12367 |
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