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Comparison of standard PCR/cloning to single genome sequencing for analysis of HIV-1 populations

To compare standard PCR/cloning and single genome sequencing (SGS) in their ability to reflect actual intra-patient polymorphism of HIV-1 populations, a total of 530 HIV-1 pro-pol sequences obtained by both sequencing techniques from a set of 17 ART naïve patient specimens was analyzed. For each spe...

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Dettagli Bibliografici
Autori principali: Jordan, Michael R., Kearney, Mary, Palmer, Sarah, Shao, Wei, Maldarelli, Frank, Coakley, Eoin P., Chappey, Colombe, Wanke, Christine, Coffin, John M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949620/
https://ncbi.nlm.nih.gov/pubmed/20451557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2010.04.030
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