Differential suppression of the aryl hydrocarbon receptor nuclear translocator-dependent function by an aryl hydrocarbon receptor PAS-A-derived inhibitory molecule

The aryl hydrocarbon receptor (AhR) heterodimerizes with the aryl hydrocarbon receptor nuclear translocator (Arnt) for transcriptional regulation. We generated three N-terminal deletion constructs of the human AhR of 12–24 KDa in size – namely D1, D2, and D3 – to suppress the Arnt function. We obser...

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Bibliografiske detaljer
Main Authors: Xie, Jinghang, Huang, Xin, Park, Miki S., Pham, Hang M., Chan, William K.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949604/
https://ncbi.nlm.nih.gov/pubmed/24486526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2014.01.021
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