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Itk-mediated integration of T cell receptor and cytokine signaling regulates the balance between Th17 and regulatory T cells
A proper balance between Th17 and T regulatory cells (T(reg) cells) is critical for generating protective immune responses while minimizing autoimmunity. We show that the Tec family kinase Itk (IL2-inducible T cell kinase), a component of T cell receptor (TCR) signaling pathways, influences this bal...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3949578/ https://ncbi.nlm.nih.gov/pubmed/24534190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131459 |
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