Transgenic kallikrein 5 mice reproduce major cutaneous and systemic hallmarks of Netherton syndrome

Netherton syndrome (NS) is a severe genetic skin disease in which absence of a key protease inhibitor causes congenital exfoliative erythroderma, eczematous-like lesions, and atopic manifestations. Several proteases are overactive in NS, including kallikrein-related peptidase (KLK) 5, KLK7, and elas...

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Bibliographic Details
Main Authors:	Furio, Laetitia, de Veer, Simon, Jaillet, Madeleine, Briot, Anais, Robin, Aurelie, Deraison, Celine, Hovnanian, Alain
Format:	Artigo
Language:	Inglês
Published:	The Rockefeller University Press 2014
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3949577/ https://ncbi.nlm.nih.gov/pubmed/24534191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131797
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Transgenic kallikrein 5 mice reproduce major cutaneous and systemic hallmarks of Netherton syndrome

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