T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow

Trail(+)DX5(−)Eomes(−) natural killer (NK) cells arise in the mouse fetal liver and persist in the adult liver. Their relationships with Trail(−)DX5(+) NK cells remain controversial. We generated a novel Eomes-GFP reporter murine model to address this question. We found that Eomes(−) NK cells are no...

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Main Authors: Daussy, Cécile, Faure, Fabrice, Mayol, Katia, Viel, Sébastien, Gasteiger, Georg, Charrier, Emily, Bienvenu, Jacques, Henry, Thomas, Debien, Emilie, Hasan, Uzma A., Marvel, Jacqueline, Yoh, Keigyou, Takahashi, Satoru, Prinz, Immo, de Bernard, Simon, Buffat, Laurent, Walzer, Thierry
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949572/
https://ncbi.nlm.nih.gov/pubmed/24516120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131560
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