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Evidence of a common mechanism of disassembly of adherens junctions through Gα13 targeting of VE-cadherin
The heterotrimeric G protein Gα13 transduces signals from G protein–coupled receptors (GPCRs) to induce cell spreading, differentiation, migration, and cell polarity. Here, we describe a novel GPCR-independent function of Gα13 in regulating the stability of endothelial cell adherens junctions (AJs)....
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3949568/ https://ncbi.nlm.nih.gov/pubmed/24590762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131190 |
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