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Follicular regulatory T cells control humoral autoimmunity via NFAT2-regulated CXCR5 expression
Maturation of high-affinity B lymphocytes is precisely controlled during the germinal center reaction. This is dependent on CD4(+)CXCR5(+) follicular helper T cells (T(FH)) and inhibited by CD4(+)CXCR5(+)Foxp3(+) follicular regulatory T cells (T(FR)). Because NFAT2 was found to be highly expressed a...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3949566/ https://ncbi.nlm.nih.gov/pubmed/24590764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130604 |
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