Population pharmacokinetics of olprinone in healthy male volunteers

BACKGROUND: Olprinone decreases the cardiac preload and/or afterload because of its vasodilatory effect and increases myocardial contractility by inhibiting phosphodiesterase III. PURPOSE: The objective of this study was to characterize the population pharmacokinetics of olprinone after a single con...

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Bibliografski detalji
Glavni autori: Kunisawa, Takayuki, Kasai, Hidefumi, Suda, Makoto, Yoshimura, Manabu, Sugawara, Ami, Izumi, Yuki, Iida, Takafumi, Kurosawa, Atsushi, Iwasaki, Hiroshi
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2014
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949558/
https://ncbi.nlm.nih.gov/pubmed/24623995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S50626
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