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Population pharmacokinetics of olprinone in healthy male volunteers
BACKGROUND: Olprinone decreases the cardiac preload and/or afterload because of its vasodilatory effect and increases myocardial contractility by inhibiting phosphodiesterase III. PURPOSE: The objective of this study was to characterize the population pharmacokinetics of olprinone after a single con...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Dove Medical Press
2014
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3949558/ https://ncbi.nlm.nih.gov/pubmed/24623995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S50626 |
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