Inducible Intestine-specific Deletion Of Krüppel-Like Factor 5 Is Characterized By A Regenerative Response In Adult Mouse Colon

Krüppel-like factor 5 (KLF5) is a pro-proliferative transcriptional regulator primarily expressed in the intestinal crypt epithelial cells. Constitutive intestine-specific deletion of Klf5 is neonatal lethal suggesting a crucial role for KLF5 in intestinal development and homeostasis. We have previo...

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Main Authors: Nandan, Mandayam O., Ghaleb, Amr M., Liu, Yang, Bialkowska, Agnieszka B., McConnell, Beth B., Shroyer, Kenneth R., Robine, Sylvie, Yang, Vincent W.
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949508/
https://ncbi.nlm.nih.gov/pubmed/24440658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.01.002
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