Krüppel-Like Factor 5 Mediates Cellular Transformation during Oncogenic KRAS-Induced Intestinal Tumorigenesis

BACKGROUND & AIMS: Krüppel-like factor 5 (KLF5) is a zinc finger-containing transcription factor that regulates cell proliferation. Oncogenic KRAS mutations are commonly found in colorectal cancers. We aimed to determine whether KLF5 mediates KRAS functions during intestinal tumorigenesis. METHO...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Nandan, Mandayam O., McConnell, Beth B., Ghaleb, Amr M., Bialkowska, Agnieszka B., Sheng, Hongmiao, Shao, Jinyi, Babbin, Brian A., Robine, Sylvie, Yang, Vincent W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194652/
https://ncbi.nlm.nih.gov/pubmed/18054006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2007.10.023
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados