Solution structure of GAP SH3 domain by 1H NMR and spatial arrangement of essential Ras signaling-involved sequence.

Src homology 3 (SH3) domains are found in numerous cytoplasmic proteins involved in intracellular signal transduction. We used 2-D 1H NMR to determine the structure of the SH3 domain of the guanosine triphosphatase-activating protein (GAP), an essential component of the Ras signaling pathway. The st...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EMBO J
Egile Nagusiak: Yang, Y S, Garbay, C, Duchesne, M, Cornille, F, Jullian, N, Fromage, N, Tocque, B, Roques, B P
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 1994
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394941/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8137811/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06379.x
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