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Insights into the Conformation of Aminofluorene-Deoxyguanine Adduct in a DNA Polymerase Active Site
The active site conformation of the mutagenic fluoroaminofluorene-deoxyguanine adduct (dG-FAF, N-(2′-deoxyguanosin-8-yl)-7-fluoro-2-aminofluorene) has been investigated in the presence of Klenow fragment of Escherichia coli DNA polymerase I (Kfexo(−)) and DNA polymerase β (pol β) using (19)F NMR, in...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3949331/ https://ncbi.nlm.nih.gov/pubmed/23798703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.476150 |
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