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Conformational and thermodynamic properties modulate the nucleotide excision repair of 2-aminofluorene and 2-acetylaminofluorene dG adducts in the NarI sequence

Nucleotide excision repair (NER) is a major repair pathway that recognizes and corrects various lesions in cellular DNA. We hypothesize that damage recognition is an initial step in NER that senses conformational anomalies in the DNA caused by lesions. We prepared three DNA duplexes containing the c...

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מידע ביבליוגרפי
Main Authors: Jain, Vipin, Hilton, Benjamin, Patnaik, Satyakam, Zou, Yue, Chiarelli, M. Paul, Cho, Bongsup P.
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351159/
https://ncbi.nlm.nih.gov/pubmed/22241773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1307
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